The ThermoFisher X Series II ICP-MS  is a quadrupole based Mass Spec for the detection of most elements in the low ppb concentration range (usually 0.2-100 ppb).  The ICP-MS is equipped with Collision Cell Technology (CCT) to reduce interferences from doublets for accurate detection of V, Cr, Fe, As, and Se.  Researchers are trained in tuning, sampling, and basic trouble shooting for unaccompanied instrument use.

FOM:   ICP-MS (QBIC)

The PerkinElmer AAnalyst 800 atomic absorption (AA) spectrometer is available within QBIC for elemental analysis of low volume samples.  The AAnalyst 800 features both a graphite furnace and flame atomization.  These atomizers are automatically exchanged within the instrument at the push of a button. Flame AA is ideal for a large number of high volume samples and higher concentration analytes. Graphite furnace AA provides ppb detection limits with < 1 mL sample volume.  The graphite furnace utilizes the patented PerkinElmer THGA tube for uniform temperature distribution & low interference.  The AAnalyst 800 also features longitudinal Zeeman background correction and automatic lamp alignment.  Available lamps: Mg, Ca, Fe, Ni, Cu, Zn, As, Pt, Au, Gd.

FOM:   Atomic Absorption Spectr -AA (QBIC)

The ThermoFisher SpectraSystem HPLC is used to separate elemental species such as As(III) and As(V), Cr compounds, Pt compounds, etc.   These species are then quantified by ICP-MS at ppt-ppb detection limits.  Visit the Photo Gallery for specific speciation examples.   The HPLC is staff run only and is not available for unaccompanied use.

FOM:   ICP-MS (QBIC)
*Specify the need for HPLC*

The Milestone EthosEZ microwave digestion system is available within QBIC for ICP-MS sample preparation.  This system is designed for closed vessel acid digestion in a fraction of the time when compared to heat blocks or other techniques.  EthosEZ vessels can withstand up to 100 bar of pressure and 260 °C.  Quartz and Teflon inserts are available for microliter sample sizes.  The rotor can hold up to 10 vessels (or 30 inserts) per run.

FOM:   Microwave Digestor (QBIC)

The ICP-MS can be coupled to the NewWave UP-213 Laser Ablation (LA) system.  The LA system uses a deep UV laser to ablate a wide range of materials, from tissue specimens to geological samples.   The aerosol produced is efficiently transported from the LA platform into the ICP-MS for elemental detection. Visit the Photo Gallery page for more examples of LA-ICP-MS.  The LA-ICP-MS is staff run only and is not available for unaccompanied use.

FOM:   ICP-MS (QBIC)
*Specify the need for LA*

The Hitachi HD-2300 STEM is equipped with dual EDX (x-ray Energy Dispersive Spectroscopy) detectors for enhanced sensitivity.  The microscope also features the Gatan Enfina 2000, electron energy-loss spectrometer (EELS). Samples can be imaged by secondary electron,  Z-contrast (annular darkfield), or transmitted electron (brightfield) detectors.  For more information about the STEM, visit the EPIC site. 

FOM:   TEM HD2300 (NUANCE)

The Inverted Zeiss Axio Observer.Z1 Confocal Microscope is ideal for a wide range of applications, including biochemistry, medical and material sciences.  The fluorescence microscope produces high resolution z-slice images with 3-D reconstruction over a wide range of wavelengths from UV to Near IR.    The Axio Observer.Z1 is completely digital providing added sensitivity and performance for exceptional quality images.  The inverted scope is equipped with a 2-photon laser (see below).

FOM:   Inverted Confocal (QBIC)

The Zeiss LSM 510 Upright Confocal Microscope is equipped with multiple laser lines for the excitation of virtually every fluorophore.  By design, the upright confocal provides an ideal platform with dipping objectives for imaging of solvent immersed samples.  The microscope is also equipped with a tunable Meta detector with multi-wavelength detection capabilities (see Photo Gallery for more information).  The upright scope is also equipped with a 2-photon laser (see below).

FOM:   Upright Confocal with META (QBIC)

Both the Upright Axio Observer.Z1 and the LSM 510 Meta are interfaced with a digitally controlled 2-photon laser (Spectra Physics Mai Tai).  This tunable Near IR pulsed laser is capable of providing excitation over the full UV and visible range for simultaneous excitation of multiple fluorophores.  2-photon imaging is ideal for live, deep-tissue microscopy by providing a low energy excitation with reduced phototoxicity.

FOM:    Inverted Confocal (QBIC) or Upright Confocal with META (QBIC)

The Zeiss SteREO Discovery.V8 fluorescence dissection microscope is now available within QBIC/CAMI. The microscope has a 8:1 zoom ratio and up to 300X magnification range with different objectives.  The X-Cite illumination system provides uniform excitation with excellent stability. Filter sets include: DAPI, GFP, Rhodamine, and Cy5.

FOM:   Fluor. Dissecting Microscope (QBIC)